What is an Autoimmune Disease?
Autoimmune disease is a broad category of conditions, where the immune system generates unwanted antibodies & cellular reactions to substances in the body. Causing the immune system to directly harm parts of the body.
Due to this immune imbalance, healthy organs of the body become damaged. Normally the immune system guards us against germs like viruses and bacteria. When it notices their presence in the body, it sends out an army of antibodies. These antibodies act as a defense against the foreign body.
Naturally, your body system is built to differentiate between foreign cells and normal cells found in your body. However, when your body is suffering from an autoimmune disease, it mistakes parts of your body (Eg. your skin or joints), as a foreigner trying to cause you harm. So it quickly responds by releasing a protein called auto-antibodies to attack and damage the healthy cells.
An autoimmune disease like “Type 1 diabetes” damages only one organ, which is the pancreas. Other autoimmune diseases for example Lupus, or Crohns Disease, affects the whole body. The original cause of autoimmune diseases can’t be fully described yet. However, some people are more prone to getting it than others. From statistics, the ratio of women to men affected by this disease is 2:1. Roughly 6.4 percent of women to 2.7 percent of men. It affects people between ages 14 to 44.
A few of these autoimmune diseases are common with some ethnic groups such as Lupus. It affects more Hispanic and African-Americans compared to Caucasians. Multiple sclerosis and lupus run in bloodlines. All family members mustn’t be affected by this disease they become vulnerable to autoimmune conditions.
Autoimmune disease is on the rise across the globe. Scientists are beginning to point hands to things that might be responsible for this disease. They suspect environmental factors like exposure to harmful chemicals and infections to be a cause. Others are suspecting diets containing high-sugar, high-fat and over processed foods as a trigger. Notwithstanding, these speculations remain unproven.
Another hypothesis by scientists is what they call, “The Hygiene Hypotheses”. This hypothesis theorizes that because of modern vaccines and antiseptics, today’s children are not exposed to as many germs, compared to kids of earlier generations. Which is why their immune systems overreact, and attack harmless body organs.
Some known early symptoms of autoimmune diseases include
- Skin Rashes
- Achy muscles
- Low-grade fever
- Swelling and redness
- Hair loss
- Having trouble concentrating
- Tingling in the hands and feet
Other individual diseases like type 1 diabetes and IBD also have their unique symptom like:
- Weight loss
- Extreme taste
- Belly pain
There are more than 80 types of autoimmune diseases known to date. Their symptoms are similar in nature, making them very hard to detect. Specialist admit, diagnosing a patient can be very frustrating. The most common symptoms include fatigue, low fever, and muscle aches. Inflammation is the most visible sign.
Using Stem Cells to Treat Autoimmune Disease
The common treatments for most autoimmune diseases include the complete use of anti-inflammatory medicines. Other powerful immunosuppressive and immunomodulatory agents are also used. Despite their effectiveness, they find it extremely difficult to induce remission with patients with consistent results. They can temporarily improve the health of the patient. This treatment method sometimes has long-term adverse effects. Resultin in the need for a life-long treatment.
Stem cell therapy is the use of stem cells to treat and prevent a diseases condition. The most commonly used stem cell therapy,in the United States, is bone marrow transplant. Stem cell therapy has undergone long-term testing on animals with numerous autoimmune disorders. The therapy has proven to induce a deep healing activity. It also has the ability to control the immune system to shut off pathological responses. At the same time, it preserves the immune system’s capacity to fight diseases. It can also heal damaged tissues.
The mesenchymal stem cells (MSC), are most common in treating autoimmune diseases. They are sourced from donated umbilical cords after normal healthy births. The mother donating each cord has to be properly screened and tested for infectious diseases. Each family has to give their consent before any donation can be made. A very small percentage of umbilical cords pass this thorough process successfully.
This cell goes through a very high quantity check process. Helping to determine cells with the best anti-inflammatory activity, the best ability to stimulate regeneration, and the best immune modulation capacity. The most effective cells being, ‘Golden cells’.
The mesenchymal stem cells produce an amazing anti-inflammatory effect. MSC’s are multi-potential and non-hematopoietic progenitor cell structures. Recently, studies show that MSC has sever beneficial effects. The two most prevalent being the immunosuppressive function and immunomodulatory properties on mismatched lymphocytes proliferation. Thus preventing suspicious cellular memory and homeopathic cells for growing & multiplying.
Some Benefits of Treating Autoimmune Disease with Allogeneic Umbilical Cord Tissue-derived Stem Cell
- There is no more need to administer chemotherapy drugs to stimulate the bone marrow in order for it to produce granulocytes and stem cells to be released into the bloodstream.
- There is evidence to show that umbilical cord-derived mesenchymal stem cells are more vigorous than mesenchymal stem cells from other sources.
- It is not necessary to collect stem cells from patient’s hip bone or fat under anaesthesia, which can be a very unpleasant ordeal for parents when it involves their child.
- In the umbilical cord tissue, you will find an abundant supply of stem cells.
- These allogeneic stem cells can be given multiple times over several days in even dosages containing high cell counts.
- During the selection process, the stem cells with the best immune modulating capacity, best anti-inflammatory activity, and regeneration stimulating ability are screened and selected.
- For the fact that HUCT mesenchymal stem cells are immune system lucky, cell rejection is never an issue and HLA matching is necessary.
During stem cell treatment, medically trained professionals will closely monitor your progress, to ensure you’re responding well. This is done specifically to evaluate overall treatment efficiency & longevity.
The process can last anywhere from 1 month to 1 Year or more.